Article
Molecular characterization of a globally distributed lineage of serotype 12F Streptococcus pneumoniae causing invasive disease.
The Journal of infectious diseases - 1 Feb 1999
Robinson D A, Turner J S, Facklam R R, Parkinson A J, Breiman R F, Gratten M, Steinhoff M C, Hollingshead S K, Briles D E, Crain M J
Abstract excerpt
These studies have identified a major genetic lineage of capsule serotype 12F Streptococcus pneumoniae, which has maintained two different types of the pneumococcal surface protein A (PspA) virulence factor and caused invasive disease in geographically disjoint locations. Twenty outbreak strains...
Topics
- Amino Acid Sequence
- Antigens, Bacterial
- Bacterial Proteins
- Base Sequence
- DNA, Bacterial
- Disease Outbreaks
- Genetic Variation
- Humans
- Molecular Sequence Data
- Pneumococcal Infections
- Polymorphism, Genetic
- Sequence Homology, Amino Acid
- Streptococcus pneumoniae
- United States