Article
Mapping of a type 1-specific and a type-common epitope on the E2 (gp53) protein of bovine viral diarrhea virus with neutralization escape mutants.
Virus research - 1 Jan 1998
Deregt D, Bolin S R, van den Hurk J, Ridpath J F, Gilbert S A
Abstract excerpt
Bovine viral diarrhoea viruses (BVDV) have recently been segregated into two genotypes, BVDV 1 and BVDV 2. However, the antigenic differences and similarities of BVDV 1 and BVDV 2 remain poorly defined. In this study, the E2 epitopes of two neutralizing monoclonal antibodies (mAbs) produced again...
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Viral
- Cross Reactions
- Diarrhea Virus 1, Bovine Viral
- Diarrhea Virus 2, Bovine Viral
- Epitope Mapping
- Molecular Sequence Data
- Mutation
- Neutralization Tests
- Viral Envelope Proteins
