Article
Sequence analysis of the DA domain of glycoprotein E2 of pestiviruses isolated from beef cattle in Southern Brazil.
Archives of virology - 1 Apr 2021
de Oliveira Freitas Carolina, de Oliveira Pablo Sebastian Britto, Monteiro Francielle Liz, Noll Jéssica Caroline Gomes, Silva Júnior José Valter Joaquim, Weiblen Rudi, Flores Eduardo Furtado
Abstract excerpt
The envelope glycoprotein E2 of pestiviruses is a major target for neutralizing antibodies. In this study, we analyzed the E2 DA domain of 43 pestiviruses from Southern Brazil. The isolates were identified as Bovine viral diarrhea virus (BVDV) subtypes 1a and 1b or BVDV-2b. Compared to reference strains, the BVDV-1 and -2 isolates had four and two mutations in the DA domain, respectively. All BVDV-2 isolates had...
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