Idiotypic specificities of rabbit anti-Salmonella abortus-equi antibodies produced by spleen cell clones involved in successive transfers in irradiated rabbits.

Abstract excerpt

Rabbits irradiated with 750 rad were reconstituted with different amounts of spleen cells from the same donor previously immunized against Salmonella abortus-equi (S. a. e.). Two limited numbers of spleen cell clones producing anti-S. a. e. antibodies were respectively expressed in two recipients of the smallest amount (5 x 10(6)) of donor spleen cells. We tried to propagate these spleen cell clones in two new...

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