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Article

Microsatellite variation in Drosophila melanogaster and Drosophila simulans: a reciprocal test of the ascertainment bias hypothesis.

Molecular biology and evolution - 1 Dec 1998

Hutter C M, Schug M D, Aquadro C F

Abstract excerpt

Interspecific comparisons of microsatellite loci have repeatedly shown that the loci are longer and more variable in the species from which they are derived (the focal species) than are homologous loci in other (nonfocal) species. There is debate as to whether this is due to directional evolution or to an ascertainment bias during the cloning and locus selection processes. This study tests these hypotheses by...

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PMID: 9866198
DOI: 10.1093/oxfordjournals.molbev.a025890

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