Article
Allelic distribution of CTG18.1 in Caucasian populations: association studies in bipolar disorder, schizophrenia, and ataxia.
Molecular psychiatry - 1 Jul 2000
McInnis M G, Swift-Scanlanl T, Mahoney A T, Vincent J, Verheyen G, Lan T H, Oruc L, Riess O, Van Broeckhoven C, Chen H, Kennedy J L, MacKinnon D F, Margolis R L, Simpson S G, McMahon F J, Gershon E, Nurnberger J, Reich T, DePaulo J R, Ross C A
Abstract excerpt
CTG18.1 is a highly polymorphic and unstable CTG repeat within an intron of the SEF2-1 gene. We tested the CTG18.1 repeat length in affective disorder, schizophrenia, and nonspecific ataxia; these diseases all have shown clinical evidence for anticipation. There was no difference in the allele frequencies comparing the controls and disease groups. The most common allele contains 11 CAGs (35%) followed by alleles...
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