Chicken anemia virus strains with a mutated enhancer/promoter region share reduced virus spread and cytopathogenicity.

doi:10.1016/s0378-1119(98)00170-x

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Article

Chicken anemia virus strains with a mutated enhancer/promoter region share reduced virus spread and cytopathogenicity.

Gene - 26 Nov 1998

Noteborn M H, Verschueren C A, van Ormondt H, van der Eb A J

Abstract excerpt

Plasmid pCAV/E contains an infectious cloned double-stranded CAV (chicken anemia virus) DNA genome (Noteborn et al., J. Virol. 65 (1991) 3131-3139). We have constructed mutated CAV genomes by introducing mutations into the CAV promoter/enhancer region of pCAV/E. Various mutated CAV strains were f...

Topics

Animals
Cells, Cultured
Chicken anemia virus
Chickens
Enhancer Elements, Genetic
Epitopes
Genome, Viral
Mutation
Promoter Regions, Genetic
T-Lymphocytes
Virus Replication

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