Article
Conditional rescue of olfactory learning and memory defects in mutants of the 14-3-3zeta gene leonardo.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Nov 2001
Philip N, Acevedo S F, Skoulakis E M
Abstract excerpt
Members of the ubiquitous 14-3-3 family of proteins are abundantly expressed in metazoan neurons. The Drosophila 14-3-3zeta gene leonardo is preferentially expressed in adult mushroom bodies, centers of insect learning and memory. Mutants exhibit defects in olfactory learning and memory and physiological neuroplasticity at the neuromuscular junction. Because strong mutations in this gene are lethal, we...
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