Article
'Mass-murder' of ORFs from three regions of chromosome XI from Saccharomyces cerevisiae.
Gene - 26 Nov 1998
Fairhead C, Thierry A, Denis F, Eck M, Dujon B
Abstract excerpt
The complete sequence of the yeast Saccharomyces cerevisiae reveals the presence of many new genes, many of which are without homologs in databases. Characterisation of these genes by novel methods includes systematic deletion followed by phenotypic analysis of mutant strains. We have developed a hierarchical strategy for such a functional analysis of genes, in which the primary phenotypic screening is performed...
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