Article
The haemochromatosis mutations do not modify the clinical picture of thalassaemia major in patients regularly transfused and chelated.
British journal of haematology - 1 Dec 1998
Borgna-Pignatti C, Solinas A, Bombieri C, Micciolo R, Gamberini M R, De Stefano P, De Menis E, Pignatti P F
Abstract excerpt
Iron overload is the main cause of morbidity and mortality in patients with thalassaemia major. In order to establish if the presence of the mutations recently described in the haemochromatosis gene affects the severity of iron overload in thalassaemia patients, we compared the prevalence of mutations C282Y and H63D in 216 young adults regularly transfused and chelated in North-Eastern Italy with the frequency...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.