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Article

Frequency of the HFE C282Y and H63D polymorphisms in Brazilian malaria patients and blood donors from the Amazon region.

Genetics and molecular research : GMR - 25 Jan 2008

Torres F R, Souza-Neiras W C, D'Almeida Couto A A, D'Almeida Couto V S C, Cavasini C E, Rossit A R B, Machado R L D, Bonini-Domingos C R

Abstract excerpt

Malaria is an endemic parasitosis and its causitive agent, Plasmodium, has a metabolism linked to iron supply. HFE is a gene with the polymorphisms C282Y and H63D, which are associated with a progressive iron accumulation in the organism leading to a disease called hereditary hemochromatosis. The aim of the present study was to determine the allelic and genotypic frequencies of the HFE gene polymorphisms in...

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Identifiers

PMID: 18273820
DOI: 10.4238/vol7-1gmr408

Genes

HFE

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