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Article

Complement component C5 and C6 mutation screening indicated in meningococcal disease in South Africa.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 23 May 2012

Owen E P, Leisegang F, Whitelaw A, Simpson J, Baker S, Würzner R, Potter P, Orren A

Abstract excerpt

BACKGROUND: Invasive meningococcal disease (MD), caused by Neisseria meningitidis infection, is endemic in South Africa, with a seasonal peak in winter and spring. There were 2 432 laboratory-confirmed cases between 2006 and 2010. Human deficiency of the fifth complement component (C5D) or complete absence of the sixth component (C6Q0) leads to increased risk of MD, which is often recurrent. All attacks are...

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PMID: 22668955
DOI: 10.7196/samj.5571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Complement component C5 and C6 mutation screening indicated in meningococcal disease in South Africa.PMID 22668955Read ↗

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