Article
Rapid synthesis of IFN-gamma by T cells in skin may play a pivotal role in the human skin immune system.
International immunology - 1 Nov 1998
Hassan-Zahraee M, Wu J, Gordon J
Abstract excerpt
This study has shown that T lymphocytes with alphabeta TCR present in normal human skin possess unique characteristics which may allow them to fulfil a unique role in skin. It disclosed that unlike T cells from blood, they are devoid of proliferative capacity in response to any ligand including lectins and phorbol esters, and show a diminished Ca2+ flux in response to phytohemagglutinin (PHA). However, despite...
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