Rapid synthesis of IFN-gamma by T cells in skin may play a pivotal role in the human skin immune system.

doi:10.1093/intimm/10.11.1599

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Article

Rapid synthesis of IFN-gamma by T cells in skin may play a pivotal role in the human skin immune system.

International immunology - 1 Nov 1998

Hassan-Zahraee M, Wu J, Gordon J

Abstract excerpt

This study has shown that T lymphocytes with alphabeta TCR present in normal human skin possess unique characteristics which may allow them to fulfil a unique role in skin. It disclosed that unlike T cells from blood, they are devoid of proliferative capacity in response to any ligand including l...

Topics

Calcium
Dactinomycin
Dendritic Cells
Flow Cytometry
Gene Expression Regulation
Humans
Interferon-gamma
Leukocytes, Mononuclear
Lymphocyte Activation
Nucleic Acid Synthesis Inhibitors
Phenotype
RNA, Messenger
Skin
T-Lymphocytes
Transcription, Genetic

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