Article
Functional GHRH receptor carboxyl terminal isoforms in normal and dwarf (dw) rats.
Journal of molecular endocrinology - 1 Dec 1998
Zeitler P, Stevens P, Siriwardana G
Abstract excerpt
GHRH plays a critical role in pituitary somatotroph development and function, actions which are mediated by a G-protein coupled receptor (GHRHr) that has been recently cloned. PCR amplification of rat pituitary mRNA using primers that span the GHRHr coding region resulted in two distinct products. When sequenced, the two isoforms were identical through bp 1278 of the GHRH coding region. However, the novel...
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