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Article

Prevalence of the factor V leiden mutation in children and neonates with thromboembolic disease.

The Journal of pediatrics - 1 Dec 1998

Hagstrom J N, Walter J, Bluebond-Langner R, Amatniek J C, Manno C S, High K A

Abstract excerpt

OBJECTIVE: Resistance to activated protein C (APC) has been identified as a risk factor for thrombotic disease in adults. In over 90% of cases, the basis for the APC resistance is a mutation in the coagulation factor V gene (factor V Leiden) that renders the protein more resistant to inactivation by APC. We sought to determine the prevalence of the factor V Leiden (FVL) mutation in neonates and children who had...

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Source

Identifiers

PMID: 9842043
DOI: 10.1016/s0022-3476(98)70150-7

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prevalence of the factor V leiden mutation in children and neonates with thromboembolic disease.PMID 9842043Read ↗

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Factor V gene mutation is a risk factor for cerebral venous thrombosis.Semantic proximity Read ↗

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