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Article

Prevalence of the factor V leiden mutation in children and neonates with thromboembolic disease.

The Journal of pediatrics - 1 Dec 1998

Hagstrom J N, Walter J, Bluebond-Langner R, Amatniek J C, Manno C S, High K A

Abstract excerpt

OBJECTIVE: Resistance to activated protein C (APC) has been identified as a risk factor for thrombotic disease in adults. In over 90% of cases, the basis for the APC resistance is a mutation in the coagulation factor V gene (factor V Leiden) that renders the protein more resistant to inactivation...

Topics

Adolescent
Adult
Child
Child, Preschool
DNA Mutational Analysis
Factor V
Humans
Infant
Infant, Newborn
Mutation
Retrospective Studies
Thromboembolism
Venous Thrombosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9842043
DOI: 10.1016/s0022-3476(98)70150-7

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9842043-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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