Postmortem DNA diagnosis of factor V Leiden in a neonate with systemic thrombosis and probable antithrombin deficiency.

doi:10.1016/s0029-7844(98)00065-9

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Article

Postmortem DNA diagnosis of factor V Leiden in a neonate with systemic thrombosis and probable antithrombin deficiency.

Obstetrics and gynecology - 1 Oct 1998

Newman R S, Spear G S, Kirschbaum N

Abstract excerpt

BACKGROUND: Spontaneous neonatal thrombosis due to heritable gene defects has been reported in the past. A recently discovered defect, the factor V Leiden mutation, is the most frequent inherited risk factor for venous thrombosis. CASE: Factor V Leiden was diagnosed postmortem in a neonate who di...

Topics

Antithrombins
Aorta, Abdominal
DNA
Factor V
Fatal Outcome
Female
Humans
Infant, Newborn
Mutation
Thrombosis
Vena Cava, Inferior

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