Article
A polymorphism in the major immediate-early gene delineates groups among cytomegalovirus clinical isolates.
Virus research - 1 Sept 1998
Retière C, Imbert B M, David G, Courcoux P, Hallet M M
Abstract excerpt
Major immediate-early gene exon 4 sequences were determined at codons 161-241 and 254-397 in 25 cytomegalovirus clinical strains and compared with those of reference strains AD169 and Towne. The nucleotide sequences at codon 161-241 segregated into three groups which could be determined by restriction mapping of a 247-nucleotide amplified target. AD169 and Towne belonged to the same group. Clustered variations...
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