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Article

Role of the C terminus of FtsK in Escherichia coli chromosome segregation.

Journal of bacteriology - 1 Dec 1998

Yu X C, Weihe E K, Margolin W

Abstract excerpt

FtsK is essential for Escherichia coli cell division. We report that cells lacking the C terminus of FtsK are defective in chromosome segregation as well as septation, often exhibiting asymmetrically positioned nucleoids and large anucleate regions. Combining the corresponding truncated ftsK gene with a mukB null mutation resulted in a synthetic lethal phenotype. When the truncated ftsK was combined with a minCDE...

Topics

Bacterial Proteins
Cell Division
Chromosomes, Bacterial
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial
Membrane Proteins
Mutation
Phenotype
Sequence Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9829960
DOI: 10.1128/JB.180.23.6424-6428.1998
PMCID: PMC107737

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Role of the C terminus of FtsK in Escherichia coli chromosome segregation.PMID 9829960Read ↗

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FtsK actively segregates sister chromosomes in Escherichia coli.Semantic proximity Read ↗

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Mutants defective in chromosome partitioning in E. coli.Semantic proximity Read ↗

A new Escherichia coli cell division gene, ftsK.Semantic proximity Read ↗

Only the N-terminal domain of FtsK functions in cell division.Semantic proximity Read ↗

MukB colocalizes with the oriC region and is required for organization of the two Escherichia coli chromosome arms into separate cell halves.Semantic proximity Read ↗

Extent of the activity domain and possible roles of FtsK in the Escherichia coli chromosome terminus.Semantic proximity Read ↗

Bacillus subtilis SepF binds to the C-terminus of FtsZ.Semantic proximity Read ↗

FtsZ and cell division.Semantic proximity Read ↗

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