Article
Only the N-terminal domain of FtsK functions in cell division.
Journal of bacteriology - 1 Sept 1998
Draper G C, McLennan N, Begg K, Masters M, Donachie W D
Abstract excerpt
Deletion of ftsK results in the inhibition of cell division, but this inhibition can be reversed by a plasmid carrying only the first approximately 17% of ftsK. The division block can be suppressed in most mutants by deletion of dacA, which codes for the D-alanine:D-alanine carboxypeptidase PBP5, or in all mutants by overexpression of ftsN. Overexpression of ftsK inhibits cell division and the formation of FtsZ...
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