Article
The sequential occurrence of viral mutations in a liver transplant recipient re-infected with hepatitis B: hepatitis B immune globulin escape, famciclovir non-response, followed by lamivudine resistance resulting in graft loss.
Journal of hepatology - 1 Oct 1998
de Man R A, Bartholomeusz A I, Niesters H G, Zondervan P E, Locarnini S A
Abstract excerpt
BACKGROUND/AIMS: The purpose of this study was to characterize the clinical, histological and virological events in an orthotopic liver transplant (OLT) recipient with recurrent hepatitis B infection who was initially managed with hepatitis B immune globulin (HBIg) and when viral recurrence occur...
Topics
- 2-Aminopurine
- Amino Acid Sequence
- Antiviral Agents
- DNA, Viral
- DNA-Directed DNA Polymerase
- Drug Resistance
- Famciclovir
- Hepatitis B
- Humans
- Immunization, Passive
- Immunoglobulins
- Lamivudine
- Liver
- Liver Transplantation