[Experimental studies and clinical significance of p53 gene mutation in carcinomas of the nasal cavity and paranasal sinuses].

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Article

[Experimental studies and clinical significance of p53 gene mutation in carcinomas of the nasal cavity and paranasal sinuses].

Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology - 1 May 1997

Yang W, Guo W, Jiang S

Abstract excerpt

By using PCR-SSCP method, 21 specimens of nasal cavity and paranasal sinuses carcinomas which were freshly frozen and paraffin embedded were detected for the mutation of p53 gene (exon 6). The overall mutation frequency of patients was 67% (14 out of 21), which was 33% (1 out of 3), 50% (3 out of...

Topics

Adenocarcinoma
Carcinoma, Squamous Cell
Genes, p53
Humans
Lymphatic Metastasis
Mutation
Nasal Cavity
Nose Neoplasms
Paranasal Sinus Neoplasms
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 9812797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9812797-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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