The three yeast A kinases have specific signaling functions in pseudohyphal growth.

doi:10.1073/pnas.95.23.13783

Back to search

Article

The three yeast A kinases have specific signaling functions in pseudohyphal growth.

Proceedings of the National Academy of Sciences of the United States of America - 10 Nov 1998

Robertson L S, Fink G R

Abstract excerpt

The three yeast A kinase catalytic subunit isoforms are redundant for viability. We demonstrate that they have dramatically different roles in pseudohyphal development: Tpk2 is essential, whereas Tpk3 inhibits. Tpk1 has no discernible effect. Two-hybrid analysis identified the transcription facto...

Topics

Cyclic AMP-Dependent Protein Kinases
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Fungal
Mutation
Saccharomyces cerevisiae
Signal Transduction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.