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Article

The three yeast A kinases have specific signaling functions in pseudohyphal growth.

Proceedings of the National Academy of Sciences of the United States of America - 10 Nov 1998

Robertson L S, Fink G R

Abstract excerpt

The three yeast A kinase catalytic subunit isoforms are redundant for viability. We demonstrate that they have dramatically different roles in pseudohyphal development: Tpk2 is essential, whereas Tpk3 inhibits. Tpk1 has no discernible effect. Two-hybrid analysis identified the transcription factor Sfl1 as a protein that interacts specifically with Tpk2, but not Tpk1 or Tpk3. Deletion of SFL1 enhances pseudohyphal...

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Identifiers

PMID: 9811878
DOI: 10.1073/pnas.95.23.13783
PMCID: PMC24897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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