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Article

Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation.

Molecular and cellular biology - 1 Jun 2002

Pan Xuewen, Heitman Joseph

Abstract excerpt

The yeast Saccharomyces cerevisiae undergoes a dimorphic filamentous transition in response to nutrient cues that is affected by both mitogen-activated protein kinase and cyclic AMP-protein kinase A signaling cascades. Here two transcriptional regulators, Flo8 and Sfl1, are shown to be the direct molecular targets of protein kinase A. Flo8 and Sfl1 antagonistically control expression of the cell adhesin Flo11 via...

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Identifiers

PMID: 12024012
DOI: 10.1128/MCB.22.12.3981-3993.2002
PMCID: PMC133872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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