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Article

hTERT is a critical determinant of telomerase activity in renal-cell carcinoma

23 Nov 1998

Abstract excerpt

Telomerase is a ribonucleoprotein enzyme which stabilizes chromosomal structure, thereby inducing cellular immortality. Three major subunits composing telomerase complex have been cloned, designated hTR (human telomerase RNA), TPI (telomerase-associated protein I), and hTERT (human telomerase reverse transcriptase). In the present study, a total of 36 renal-cell carcinomas (RCC) and adjacent normal tissues, as...

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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9808519
DOI: 10.1002/(sici)1097-0215(19981123)78:5<539::aid-ijc2>3.0.co;2-i

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