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Article

Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues

5 Jan 1999

Abstract excerpt

Telomerase activation is thought to be essential for cellular immortality and oncogenesis. It is observed in most malignant tumors but not in most normal somatic tissues. Normal human endometrium is, however, known to express significant telomerase activity in a menstrual phase-dependent manner. The 3 major subunits composing telomerase have been identified. Using normal and malignant endometrial tissues, we...

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Identifiers

PMID: 9935231
DOI: 10.1002/(sici)1097-0215(19990105)80:1<60::aid-ijc12>3.0.co;2-e

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