Article
HiNF-D (CDP-cut/CDC2/cyclin A/pRB-complex) influences the timing of IRF-2-dependent cell cycle activation of human histone H4 gene transcription at the G1/S phase transition.
Journal of cellular physiology - 1 Dec 1998
Aziz F, van Wijnen A J, Stein J L, Stein G S
Abstract excerpt
Cell cycle control of histone H4 gene transcription is mediated by the multipartite promoter domain H4-Site II, which supports transcriptional activation at the G1/S phase transition and modulates basal H4 gene transcription. Proliferation-specific transcription is determined by the integrated ac...
Topics
- Base Sequence
- Binding Sites
- Cell Cycle
- Choline O-Acetyltransferase
- DNA-Binding Proteins
- G1 Phase
- Histones
- Humans
- Interferon Regulatory Factor-2
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- RNA, Messenger
- Repressor Proteins
- S Phase
- Time Factors
- Transcription Factors
- Transcription, Genetic