Article
Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by gamma-linolenic acid administration.
Metabolism: clinical and experimental - 1 Sept 1993
Phinney S D, Tang A B, Thurmond D C, Nakamura M T, Stern J S
Abstract excerpt
Below-normal proportions of phospholipid (PL) arachidonic acid (20:4 omega 6) have been reported in serum from obese humans and in liver from obese Zucker rats. This implies an abnormality of 20:4 omega 6 formation from linoleic acid (18:2 omega 6), possibly in the delta 6 desaturase step, or alt...
Topics
- Adipose Tissue
- Animals
- Dietary Fats, Unsaturated
- Fatty Acids, Essential
- Genotype
- Lipid Metabolism
- Liver
- Male
- Obesity
- Rats
- Rats, Zucker
- Reference Values
