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Article

Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus.

Molecular and biochemical parasitology - 15 Sept 1998

Blackhall W J, Liu H Y, Xu M, Prichard R K, Beech R N

Abstract excerpt

Resistance to anthelmintics that are used to control parasite populations in domestic animals has become a serious problem worldwide. The development of resistance is an evolutionary process that leads to genetic changes in parasite populations in response to drug exposure. The anthelmintic ivermectin is known to bind to the human membrane transport protein, P-glycoprotein, and P-glycoprotein-deficient mice...

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Source

Identifiers

PMID: 9803412
DOI: 10.1016/s0166-6851(98)00087-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus.PMID 9803412Read ↗

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Comparison of P-glycoprotein gene expression of two Haemonchus contortus isolates from Yucatan, Mexico, with resistant or susceptible phenotype to ivermectin in relation to a susceptible reference strain.Semantic proximity Read ↗

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The use of DNA markers to map anthelmintic resistance loci in an intraspecific cross of Haemonchus contortus.Semantic proximity Read ↗

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