Article
Identification of three new DRB3* (DRB3*0106, DRB3*0107 and DRB3*02022) alleles.
Tissue antigens - 1 Apr 2001
Tavoularis S, Ouellet S, Stephens S
Abstract excerpt
Three novel DRB3* alleles were identified using CANTYPE reverse hybridization assay. The initial unusual hybridization patterns of DRB3-specific polymerase chain reaction (PCR)-amplified DNA from each subject were confirmed by cloning and sequencing analysis. DRB3*0106 allele is identical to DRB3*0101 except for a single nucleotide substitution (CTG-->GTG) changing codon 38 from Leu to Val. This polymorphism is...
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