Article
Tumor necrosis factor-beta is associated with thymic apoptosis during acute rejection.
Transplantation - 15 Oct 1998
Yamaguchi Y, Okabe K, Miyanari N, Matsumura F, Ichiguchi O, Akizuki E, Matsuda T, Liang J, Ohshiro H, Miyayama Y, Yamada S, Mori K, Ogawa M
Abstract excerpt
BACKGROUND: Intrathymic events undergoing allograft rejection remain undefined. The present study investigated the role of tumor necrosis factor-beta on acute thymic involution in rat hepatic allograft recipients during rejection. METHODS: Apoptosis and cellular phenotypic changes in the thymus w...
Topics
- Acute Disease
- Animals
- Apoptosis
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Size
- Flow Cytometry
- Graft Rejection
- Humans
- Interleukin-10
- Liver Transplantation
- Lymphotoxin-alpha
