Article
Effect of disruption of a gene encoding an autolysin of Enterococcus faecalis OG1RF.
Antimicrobial agents and chemotherapy - 1 Nov 1998
Qin X, Singh K V, Xu Y, Weinstock G M, Murray B E
Abstract excerpt
A mutant (TX5127) of Enterococcus faecalis OG1RF was generated by disruption mutagenesis of a previously described autolysin gene. TX5127 formed longer chains (2 to 10 cells per chain) than wild-type OG1RF (mainly single cells) during growth in broth even though it had a growth rate similar to th...
Topics
- Animals
- Enterococcus faecalis
- Female
- Mice
- Mice, Inbred ICR
- Mutation
- N-Acetylmuramoyl-L-alanine Amidase
- Penicillins
- Peritonitis
- Virulence