Article
Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model.
The Journal of infectious diseases - 1 Nov 1998
Singh K V, Qin X, Weinstock G M, Murray B E
Abstract excerpt
A previously described mouse peritonitis model was used to study derivatives of Enterococcus faecalis strain OG1RF. The addition of sterile rat fecal extracts (SRFE) lowered the LD50 of OG1RF >10-fold. Hemolysin production caused a 35-fold lower LD50 and a much shorter survival, similar to previo...
Topics
- Animals
- Disease Models, Animal
- Enterococcus faecalis
- Feces
- Female
- Gelatinases
- Gram-Positive Bacterial Infections
- Hemolysin Proteins
- Mice
- Mutation
- Peritonitis
- Rats