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Article

Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model.

The Journal of infectious diseases - 1 Nov 1998

Singh K V, Qin X, Weinstock G M, Murray B E

Abstract excerpt

A previously described mouse peritonitis model was used to study derivatives of Enterococcus faecalis strain OG1RF. The addition of sterile rat fecal extracts (SRFE) lowered the LD50 of OG1RF >10-fold. Hemolysin production caused a 35-fold lower LD50 and a much shorter survival, similar to previous results using a peritonitis model without SRFE. A purine (but not a pyrimidine) auxotroph was considerably less...

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Identifiers

PMID: 9780263
DOI: 10.1086/314453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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