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Article

Haldane's rule in taxa lacking a hemizygous X.

Science (New York, N.Y.) - 30 Oct 1998

Presgraves D C, Orr H A

Abstract excerpt

Haldane's rule states that species hybrids of the XY sex are preferentially sterile or inviable. In all taxa known to obey this rule, the Y is inert and X-linked genes show full expression in XY individuals. Until recently, all theories of Haldane's rule depended on this hemizygosity. A test of Haldane's rule in animals lacking a hemizygous sex-mosquitoes having two functional sex chromosomes in both...

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PMID: 9794768
DOI: 10.1126/science.282.5390.952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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