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Article

Physiological sex predicts hybrid sterility regardless of genotype.

Science (New York, N.Y.) - 4 Jan 2008

Malone John H, Michalak P

Abstract excerpt

Reproductive isolation between biological species is characterized by Haldane's rule, which states that the heterogametic sex (XY or ZW) suffers the most dysfunctional effects of hybridization. It has been hypothesized that, in addition to X-linked recessive genes, Haldane's rule also reflects the faster evolution of genes related to male reproduction (faster-male evolution). We used sex-reversed hybrid Xenopus...

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Identifiers

PMID: 18174434
DOI: 10.1126/science.1148231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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