Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The dominance theory of Haldane's rule.

Genetics - 1 May 1995

Turelli M, Orr H A

Abstract excerpt

"HALDANE's rule" states that, if species hybrids of one sex only are inviable or sterile, the afflicted sex is much more likely to be heterogametic (XY) than homogametic (XX). We show that most or all of the phenomena associated with HALDANE's rule can be explained by the simple hypothesis that alleles decreasing hybrid fitness are partially recessive. Under this hypothesis, the XY sex suffers more than the XX...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dosage Compensation, Genetic
Share to Alleles
Share to Genes, Dominant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Lethal

Share to Genes, Recessive

Share to Hybridization, Genetic

Share to Mammals

Share to Models, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7635302
DOI: 10.1093/genetics/140.1.389
PMCID: PMC1206564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The dominance theory of Haldane's rule.PMID 7635302Read ↗

Haldane's rule in taxa lacking a hemizygous X.Semantic proximity Read ↗

Sexually antagonistic "zygotic drive" of the sex chromosomes.Semantic proximity Read ↗

Gene flow across a hybrid zone maintained by a weak heterogametic incompatibility and positive selection of incompatible alleles.Semantic proximity Read ↗

The diverse effects of phenotypic dominance on hybrid fitness.Semantic proximity Read ↗

Transformation of meiotic drive into hybrid sterility in DrosophilaSemantic proximity Read ↗

Dominance reversals and the maintenance of genetic variation for fitness.Semantic proximity Read ↗

Evolutionary inevitability of sexual antagonism.Semantic proximity Read ↗

Mutation-selection balance, dominance and the maintenance of sex.Semantic proximity Read ↗

Gene-rich X chromosomes implicate intragenomic conflict in the evolution of bizarre genetic systemsSemantic proximity Read ↗

Revisiting Dominance in Population Genetics.Semantic proximity Read ↗

Causes of Sex Ratio Bias may Account for Unisexual Sterility in Hybrids: A New Explanation of Haldane's Rule and Related PhenomenaSemantic proximity Read ↗

Differential barrier strength and allele frequencies in hybrid zones maintained by sex-biased hybrid incompatibilities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.