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Article

[Haldane's rule and somatic mutations].

Genetika - 1 Jun 1999

Gorshkov V G, Makar'eva A M

Abstract excerpt

Haldane's rule stating that viability and fertility in the heterogametic sex of hybrids are lower than in the homogametic sex is explained on the basis of the assumption that diploidy is aimed at protecting individuals having large body size and large genomes from somatic mutations. The presence of hemizygous sex chromosomes, which are effectively haploid in the heterogametic sex, results in the phenotypic...

Topics

Heterozygote
Models, Genetic
Mutation
Sex Determination Processes
X Chromosome

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10505261

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