The StuI polymorphism on exon 8 of the low density lipoprotein (LDL) receptor gene: prevalence and impact on serum lipid levels in an Asian cohort.

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Article

The StuI polymorphism on exon 8 of the low density lipoprotein (LDL) receptor gene: prevalence and impact on serum lipid levels in an Asian cohort.

Annals of the Academy of Medicine, Singapore - 1 Jul 1998

Choong M L, Sethi S K, Koay E S

Abstract excerpt

A single nucleotide (A-->G) substitution in codon 370 (exon 8) of the low density lipoprotein (LDL) receptor gene results in loss of a StuI restriction site and an amino acid change (Ala370-->Thr) in the translated protein. This biallelic polymorphism has been associated with significant variatio...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Cohort Studies
Deoxyribonucleases, Type II Site-Specific
Ethnicity
Exons
Female
Gene Frequency
Genotype
Humans
Lipids
Male
Middle Aged
Polymorphism, Genetic
Receptors, LDL

Source

Open in PubMed

Identifiers

PMID: 9791654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9791654-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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