Article
Isoelectrofocusing phenotype and relative concentration of transcobalamin II isoproteins related to the codon 259 Arg/Pro polymorphism.
Biochemical and biophysical research communications - 29 Oct 1998
Namour F, Guy M, Aimone-Gastin I, de Nonancourt M, Mrabet N, Guéant J L
Abstract excerpt
We investigated transcobalamin II (TC) isoelectrofocusing (IEF) phenotype and codon 259 polymorphism, in Caco-2 and HT-29 cells and in blood drawn from 39 healthy Caucasians. Caco-2 cells expressed a single TC variant (259-Arg), while HT-29 cells expressed TC with either Arg or Pro at codon 259 a...
Topics
- Adult
- Aged
- Apoproteins
- Arginine
- Caco-2 Cells
- HT29 Cells
- Heterozygote
- Homozygote
- Humans
- Isoelectric Focusing
- Middle Aged
- Neoplasm Proteins
- Phenotype
- Polymorphism, Genetic
- Proline
- Protein Isoforms
- Transcobalamins
- Vitamin B 12