Article
Protein phosphatase 2A is involved in hyphal growth of Neurospora crassa.
Molecular & general genetics : MGG - 1 Sept 1998
Yatzkan E, Szöor B, Fehér Z, Dombrádi V, Yarden O
Abstract excerpt
Cantharidin and calyculin A, natural toxins that are inhibitors of protein phosphatases 1 and 2A (PPI and PP2A, respectively). inhibit Neurospora crassa hyphal growth. When N. crassa was grown in the presence of either drug, abnormalities were observed at hyphal tips. In addition, both drugs induced an increase in hyphal branching. Cantharidin inhibited N. crassa hyphal growth in a temperature-dependent manner,...
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