Mutational activation of a Galphai causes uncontrolled proliferation of aerial hyphae and increased sensitivity to heat and oxidative stress in Neurospora crassa.

doi:10.1093/genetics/151.1.107

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Article

Mutational activation of a Galphai causes uncontrolled proliferation of aerial hyphae and increased sensitivity to heat and oxidative stress in Neurospora crassa.

Genetics - 1 Jan 1999

Yang Q, Borkovich K A

Abstract excerpt

Heterotrimeric G proteins, consisting of alpha, beta, and gamma subunits, transduce environmental signals through coupling to plasma membrane-localized receptors. We previously reported that the filamentous fungus Neurospora crassa possesses a Galpha protein, GNA-1, that is a member of the Galpha...

Topics

Alleles
Carotenoids
Cyclic AMP
GTP Phosphohydrolases
GTP-Binding Protein alpha Subunits, Gi-Go
Heating
Hydrogen Peroxide
Mutation
Neurospora crassa
Osmosis
Oxidative Stress

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