Article
Mutants with altered sensitivity to a calmodulin antagonist affect the circadian clock in Neurospora crassa.
Genetics - 1 Jul 1996
Suzuki S, Katagiri S, Nakashima H
Abstract excerpt
Two newly isolated mutant strains of Neurospora crassa, cpz-1 and cpz-2, were hypersensitive to chlorpromazine with respect to mycelial growth but responded differently to the drug with respect to the circadian conidiation rhythm. In the wild type, chlorpromazine caused shortening of the period length of the conidiation rhythm. Pulse treatment with the drug shifted the phase and inhibited light-induced phase...
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