Article
Polymerase chain reaction analysis of the Y chromosome long arm in azoospermic patients: lack of the Y chromosome recognition motif (YRRM1) gene.
International journal of urology : official journal of the Japanese Urological Association - 1 Sept 1998
Baba K, Iwamoto T, Nakagome Y, Kuroki Y, Nakahori Y, Yajima M, Tanaka H, Osada T
Abstract excerpt
We analyzed DNA from a patient with azoospermia whose Y chromosome was cytogenetically normal. A total of 16 loci on the Y chromosome long arm were examined: 15 loci between DYS7E and DYZ1, and the Y chromosome RNA recognition motif (YRRM1) locus, a candidate gene for the azoospermic factor AZF. We did not detect the YRRM1 gene in this patient. This finding supports the theory that YRRM1 is an essential gene for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.