Article
Concentrations of the atherogenic Lp(a) are elevated in FH.
European journal of human genetics : EJHG - 1 Jan 1998
Lingenhel A, Kraft H G, Kotze M, Peeters A V, Kronenberg F, Kruse R, Utermann G
Abstract excerpt
Lipoprotein(a) (Lp(a)) is a complex in human plasma assembled from low-density lipoprotein (LDL) and apolipoprotein(a) (apo(a)). High plasma concentrations of Lp(a) are a risk factor for coronary heart disease (CHD) in particular in patients with concomitant elevation of LDL. We have analysed for elevated Lp(a) levels in patients with familial hypercholesterolaemia (FH), a condition caused by mutations in the LDL...
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