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Article

Effects of Bacterial DNA on Cytokine Production by (NZB/NZW)F1 Mice

1 Oct 1998

Abstract excerpt

Microbial DNA has multiple immune effects including the capacity to induce polyclonal B cell activation and cytokine production in normal mice. We recently described the accelerated induction of anti-DNA Abs in NZB/NZW mice immunized with Escherichia coli (EC) dsDNA; paradoxically these mice developed less renal disease than unimmunized mice or mice immunized with calf thymus DNA. We postulated that alterations...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 9780154
DOI: 10.4049/jimmunol.161.8.3890

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