Familial defective apolipoprotein B-100.

Article

Familial defective apolipoprotein B-100.

Danish medical bulletin - 1 Sept 1998

Hansen P S

Abstract excerpt

Abnormal interaction between low density lipoprotein receptors (LDLR) and their ligands, apolipoprotein E and B, causes decreased catabolism of lipoproteins which carry these apolipoproteins (VLDL, IDL and/or LDL) and thereby increased plasma concentrations of these. In familial hypercholesterole...

Topics

Animals
Apolipoprotein B-100
Apolipoproteins B
Female
Humans
Hyperlipoproteinemia Type II
Male
Mutation
Pedigree
Rats

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