Article
Functional phylogeny: the use of the sensitivity of ribosomes to protein synthesis inhibitors as a tool to study the evolution of organisms.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life - 1 Oct 1998
Briones C, Koroutchev K, Amils R
Abstract excerpt
In order to study the functional phylogeny of organisms, forty different protein synthesis inhibitors with diverse domain and functional specificities have been used to analyze forty archaeal, bacterial and eukaryotic translational systems. The inhibition curves generated with the different ribos...
Topics
- Animals
- Archaea
- Bacteria
- Biological Evolution
- Eukaryotic Cells
- Genotype
- Mathematics
- Models, Biological
- Phylogeny
- Protein Biosynthesis
- Protein Synthesis Inhibitors
- RNA, Ribosomal, 16S
- RNA, Ribosomal, 18S
- Ribosomes