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Article

Colonic epithelial cell proliferation in hereditary non-polyposis colorectal cancer.

Gut - 1 Jul 1998

Green S E, Chapman P, Burn J, Burt A D, Bennett M, Appleton D R, Varma J S, Mathers J C

Abstract excerpt

BACKGROUND: Despite the recent discovery of four genes responsible for up to 90% of all cases of hereditary non-polyposis colorectal cancer (HNPCC), there will still be families in whom predictive testing is not possible. A phenotypic biomarker would therefore be useful. An upwards shift of the proliferative compartment in colonic crypts is reported to be one of the earliest changes in premalignant mucosa. AIMS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9771410
DOI: 10.1136/gut.43.1.85
PMCID: PMC1727161

Genes

MIB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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