Article
Phenotype and genotype in polycystic ovary syndrome.
Recent progress in hormone research - 1 Jan 1998
Legro R S, Spielman R, Urbanek M, Driscoll D, Strauss J F, Dunaif A
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common disorder in premenopausal women and is characterized by hyperandrogenic chronic anovulation. The cause is unknown. PCOS is associated with significant insulin resistance as well as with defects in insulin secretion. These abnormalities place these women at substantial risk for developing type 2 diabetes mellitus. A defect in insulin-mediated receptor...
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