Expression of ptsG, the gene for the major glucose PTS transporter in Escherichia coli, is repressed by Mlc and induced by growth on glucose.

doi:10.1046/j.1365-2958.1998.00991.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Expression of ptsG, the gene for the major glucose PTS transporter in Escherichia coli, is repressed by Mlc and induced by growth on glucose.

Molecular microbiology - 1 Aug 1998

Plumbridge J

Abstract excerpt

The gene for the glucose-specific transporter of the phosphotransferase system, ptsG, is expressed from two promoters separated by 141 bp. The expression of the major, shorter transcript is very strongly dependent upon cAMP/CAP. However, unlike other CAP-activated genes, the expression of ptsG is...

Topics

Bacterial Proteins
Base Sequence
Binding Sites
Cyclic AMP
Cyclic AMP Receptor Protein
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Genes, Bacterial
Glucose
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phosphoenolpyruvate Sugar Phosphotransferase System

Promoter Regions, Genetic

RNA, Bacterial

RNA, Messenger

Repressor Proteins

Source

Open in PubMed

Identifiers

PMID: 9767573
DOI: 10.1046/j.1365-2958.1998.00991.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9767573-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of ptsG, the gene for the major glucose PTS transporter in Escherichia coli, is repressed by Mlc and induced by growth on glucose.PMID 9767573Read ↗

Negative regulation of the pts operon by Mlc: mechanism underlying glucose induction in Escherichia coli.Semantic proximity Read ↗

Glycerol-3-phosphate-mediated repression of malT in Escherichia coli does not require metabolism, depends on enzyme IIAGlc and is mediated by cAMP levels.Semantic proximity Read ↗

External-pH-dependent expression of the maltose regulon and ompF gene in Escherichia coli is affected by the level of glycerol kinase, encoded by glpK.Semantic proximity Read ↗

Expression of ptsG encoding the major glucose transporter is regulated by ArcA in Escherichia coli.Semantic proximity Read ↗

Glucose- and glucokinase-controlled mal gene expression in Escherichia coli.Semantic proximity Read ↗

A novel regulatory role of glucose transporter of Escherichia coli: membrane sequestration of a global repressor Mlc.Semantic proximity Read ↗

A mutation which affects both the specificity of PtsG sugar transport and the regulation of ptsG expression by Mlc in Escherichia coli.Semantic proximity Read ↗

Signal transduction between a membrane-bound transporter, PtsG, and a soluble transcription factor, Mlc, of Escherichia coli.Semantic proximity Read ↗

A new carbon catabolite repression mutation of Escherichia coli, mlc∗, and its use for producing isobutanol.Semantic proximity Read ↗

The repressor Rgt1 and the cAMP-dependent protein kinases control the expression of the SUC2 gene in Saccharomyces cerevisiae.Semantic proximity Read ↗

Positive regulation of the expression of the Escherichia coli pts operon. Identification of the regulatory regions.Semantic proximity Read ↗

Characterization of glucose-repression-resistant mutants of Bacillus subtilis: identification of the glcR gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.