Article
Risk of population extinction from fixation of deleterious and reverse mutations.
Genetica - 1 Jan 1998
Lande R
Abstract excerpt
A model is developed for alternate fixations of mildly deleterious and wild-type alleles arising by forward and reverse mutation in a finite population. For almost all parameter values, this gives an equilibrium load that agrees closely with the general expression derived from diffusion theory. N...
Topics
- Animals
- Genetic Variation
- Models, Genetic
- Models, Statistical
- Mutation
- Population Dynamics
- Risk Assessment
